Both David Kahn and Simon Singh make reference to Giovanni Soro: "Arguably the first great European cryptanalyst was Giovanni Soro, appointed as Venetian cipher secretary in 1506." (Singh). Kahn calls him "perhaps the West's first great cryptanalist".
It seems that he ran THE cryptanalisis operation under the control of the mysterious Council of the Ten, to which even the Vatican was second. In 1542, his offices, according to Kahn in 'The Codebreakers', were in "the Doge's Palace, above the Sala di Segret".
His treatise on cryptology, written in the early 1500s is one of the Lost Books of cryptology... something like the Amber Room of the Cinquecento ciphers.
Nick, do we know if this man ever corresponded with Mr Simonetta from the Milano Sforzas?